Nutramedix, MORA- MICROBIAL DEFENSE

Mora is a proprietary blend of the extracts of three plants Blackberry, Capirona, and Yarrow. Traditionally, Yarrow (Achillea millefolium) has been used to treat a number of medical conditions. It was used to help stop minor bleeding and to treat wounds, to treat inflammation in a number of conditions, fight fevers, treat gastrointestinal conditions, lessen heavy menstrual bleeding, and improve circulation. Some of the compounds found in Yarrow that may explain its medicinal benefits are apigenin, luteolin, centaureidin, casticin, artemetin, paulitin, isopaulitin, psilostachyin, desacetylmatricarin and sintenin.  Traditionally, blackberry leaf tea (Rubus fruticosus) has been used to treat parasites and Capirona (Calycophyllum spruceanum) to treat diabetes, soothe the skin and for fungal, bacterial and parasitic infections.

ANTI-PARASITIC

ANTI-BACTERIAL

ANTI-FUNGAL

ANTI-MOTILITY EFFECT

ANTI-OXIDANT ACTIVITY

ANTI-NOCICEPTIVE EFFECT (increases 

tolerance for pain)

ESTROGENIC ACTIVITY

CHOLERETIC EFFECT

CYTOPROTECTIVE

ADJUNCTIVE TO CHEMOTHERAPY

Miranzadeh,S., Adib-Hajbaghery, M., Soleymanpoor, L., & Ehsani, M. (2015). Effect of adding the herb Achilleamillefolium on mouthwash on chemotherapy induced oral mucositis in cancer patients: A double-blind randomized controlled trial. European Journal of Oncology Nursing, 19(3), 207-213. Full Article

ANXIETY

Fernández-Demeneghi, R., Rodríguez-Landa, J. F., Guzmán-Gerónimo,R. I., Acosta-Mesa, H. G., Meza-Alvarado, E., Vargas-Moreno, I., &Herrera-Meza, S. (2019). Effect of blackberry juice (Rubus fruticosus L.) on anxiety-like behaviour in Wistar rats. International journal of food sciences and nutrition, 1-12. Full Article

CANCER

Amini Navaie, B., Kavoosian, S., Fattahi, S., Hajian-Tilaki, K., Asouri, M.,Bishekolaie, R., & Akhavan-Niaki, H. (2015). Antioxidant and cytotoxic effect of aqueous and hydroalcoholic extracts of the Achillea millefolium L. on MCF-7 breast cancer cell line. International Biological and Biomedical Journal, 1(3), 119-125. Full Article

ANTIOXIDANT

Villalva, M., Jaime, L., Villanueva-Bermejo,D., Lara, B., Fornari, T., Reglero, G., & Santoyo, S. (2019). Supercritical anti-solvent fractionation for improving antioxidant and anti-inflammatory activities of an Achillea millefolium L. extract. Food Research International, 115, 128-134. Full Article

Monforte, M. T., Smeriglio, A.,Germanò, M. P., Pergolizzi, S., Circosta, C., & Galati, E. M. (2018). Evaluation of antioxidant, antiinflammatory, and gastroprotective properties of Rubus fruticosus L. fruit juice. Phytotherapy research, 32(7), 1404-1414. Full Article

ANTITUMOR

Pereira, J. M., Peixoto, V., Teixeira,A., Sousa, D., Barros, L., Ferreira, I. C., & Vasconcelos, M. H.(2018). Achillea millefolium L. hydroethanolic extract inhibits growth of human tumor cell lines by interfering with cell cycle and inducing apoptosis. Food and Chemical Toxicology. Full Article

ANTIMUTAGENIC

Hussein, A. A., Al-Ezzy, R. M., & Abdallah, M. T. (2019). Biochemical, Enzymatic, and Immunological Study on Antimutagenic Achillea millefolium Methanolic Extract in vivo. Journal of Pharmacy and Pharmacology,7, 69-74. Full Article

MULTIPLE SCLEROSIS

Ayoobi, F., Moghadam-Ahmadi, A.,Amiri, H., Vakilian, A., Heidari, M., Farahmand, H., ... & Shamsizadeh, A.(2019). Achillea millefolium is beneficial as an add-on therapy in patients with multiple sclerosis: A randomized placebo-controlled clinical trial. Phytomedicine, 52, 89-97. Full Article

ANTI-INFLAMMATORY

Benedek, B., Kopp, B., & Melzig, M. F. (2007). Achillea millefolium L. sl–Is the anti-inflammatory activity mediated by protease inhibition?. Journal of Ethnopharmacology, 113(2), 312-317. Full Article

Benedek, B., & Kopp, B. (2007). Achillea millefolium L. sl revisited: recent findings confirm the traditional use. Wiener Medizinische Wochenschrift, 157(13-14), 312-314. Full Article

ANTIBACTERIAL

Thanina, A. C., Mourad, B. E. N. D. A. H. O. U., & Karim, A. R. A. B. (2015). Antibacterial activity of two extracts from Rubus fruticosus L. against resistant pathogens and their antioxidant potential. African Journal of Microbiology Research, 9(18), 1255-1262. Full Article

Yakhkeshi, S., Rahimi, S., & Hemati Matin, H. R. (2012). Effects of yarrow (Achillea millefolium L.), antibiotic and probiotic on performance, immune response, serum lipids and microbial population of broilers. Journal of Agricultural Science and Technology, 14(4), 799-810. Full Article

Novaković, A. R., Radusin, T. I., Tomšik, A. M., & Ikonić, P.M. (2018). PLA films loaded with Achillea millefolium: In vitro antibacterial effects. Food and Feed Research, 45(1), 45-52. Full Article

ANTIMICROBIAL

Riaz, M., Ahmad, M., & Rahman, N. (2011). Antimicrobial screening of fruit, leaves, root and stem of Rubus fruticosus. Journal of Medicinal Plants Research, 5(24), 5920-5924. Full Article

Shahbazi, Y., & Zadeh, M. S. (2008). In vitro assessment of antimicrobial efficacy of alcoholic extract of Achillea millefolium in comparison with penicillin derivatives. J Anim Vet Adv, 7(4), 508-11. Full Article

Candan, F., Unlu, M., Tepe, B., Daferera, D., Polissiou, M., Sökmen, A., & Akpulat, H. A. (2003). Antioxidant and antimicrobial activity of the essential oil and methanol extracts of Achillea millefolium subsp. millefolium Afan.(Asteraceae). Journal of Ethnopharmacology, 87(2-3), 215-220. Full Article

ANTIOXIDANT

Zafra-Rojas, Q., Cruz-Cansino, N., Delgadillo-Ramírez, A., Alanís-García, E., Añorve-Morga, J., Quintero-Lira, A., ... & Ramírez-Moreno, E. (2018). Organic Acids, Antioxidants, and Dietary Fiber of Mexican Blackberry (Rubus fruticosus) Residues cv. Tupy. Journal of Food Quality, 2018. Full Article

Barut, E. N., Barut, B., Engin, S., Yıldırım, S., Yaşar, A., Türkiş, S., ... & Sezen, F. S. (2017). Antioxidant capacity, anti-acetylcholinesterase activity and inhibitory effect on lipid peroxidation in mice brain homogenate of Achillea millefolium. Turkish Journal of Biochemistry, 42(4), 493-502. Full Article

Becker, L., Zaiter, A., Petit, J., Zimmer, D., Karam, M. C., Baudelaire, E., ... & Dicko, A. (2016). Improvement of antioxidant activity and polyphenol content of Hypericum perforatum and Achillea millefolium powders using successive grinding and sieving. Industrial Crops and Products, 87, 116-123. Full Article

Georgieva, L., Gadjalova, A., Mihaylova, D., & Pavlov, A. (2015). Achillea millefolium L.-phytochemical profile and in vitro antioxidant activity. International Food Research Journal, 22(4), 1347. Full Article

Fierascu, I., Ungureanu, C., Avramescu, S. M., Fierascu, R. C., Ortan, A., Soare, L. C., & Paunescu, A. (2015). In vitro antioxidant and antifungal properties of Achillea millefolium L. Rom Biotechnol Lett, 20, 10626-36. Full Article

Bhagat, M., & Thusoo, S. (2015). Phytochemical, Cytotoxic and Immunomodulatory Analysis of an Indian Blackberry Rubus fruticosus. Journal of Biologically Active Products from Nature, 5(5), 339-348. Full Article

Asnaashari, M., Tajik, R., & Khodaparast, M. H. H. (2015). Antioxidant activity of raspberry (Rubus fruticosus) leaves extract and its effect on oxidative stability of sunflower oil. Journal of food science and technology, 52(8), 5180-5187. Full Article

Trumbeckaite, S., Benetis, R., Bumblauskiene, L., Burdulis, D., Janulis, V., Toleikis, A., ... & Jakštas, V. (2011). Achillea millefolium L. sl herb extract: Antioxidant activity and effect on the rat heart mitochondrial functions. Food Chemistry, 127(4), 1540-1548. Full Article

Potrich, F. B., Allemand, A., da Silva, L. M., dos Santos, A. C., Baggio, C. H., Freitas, C. S., ... & Marques, M. C. A. (2010). Antiulcerogenic activity of hydroalcoholic extract of Achillea millefolium L.: involvement of the antioxidant system. Journal of Ethnopharmacology, 130(1), 85-92. Full Article

Giorgi, A., Mingozzi, M., Madeo, M., Speranza, G., & Cocucci, M. (2009). Effect of nitrogen starvation on the phenolic metabolism and antioxidant properties of yarrow (Achillea collina Becker ex Rchb.). Food Chemistry, 114(1), 204-211. Full Article

Teixeira, R. D. O., Camparoto, M. L., Mantovani, M. S., & Vicentini, V. E. P. (2003). Assessment of two medicinal plants, Psidium guajava L. and Achillea millefolium L., in vitro and in vivo assays. Genetics and Molecular Biology, 26(4), 551-555. Full Article

Santos, S. S., Rodrigues,L. M., Costa, S. C., & Madrona, G. S. (2017). Antioxidant compounds from blackberry (Rubus fruticosus) pomace: Microencapsulation by spray-dryer and pH stability evaluation. Food Packaging and Shelf Life. Full Article

García-Risco, M. R., Mouhid, L., Salas-Pérez, L., López-Padilla,A., Santoyo, S., Jaime, L., ... & Fornari, T. (2017). Biological activities of Asteraceae (Achillea millefolium and Calendula officinalis) and Lamiaceae (Melissa officinalis and Origanum majorana) plant extracts. Plant foods for human nutrition, 72(1), 96-102. Full Article

ANTIDIARRHOEL

Bais, S., Gill, N. S., & Shandil, S. (2014). Antidiarrhoel activity of methanolic extract of Achillea millefolium L. leaves in albino rats. Der Pharma Chemica, 6(5), 308-14. Full Article

ANTIFUNGAL

 Aydın, S., & Sevindik, E. (2018). Achillea millefolium L. subsp. millefolium essential oil’s antifungal effect. European Journal of Biological Research, 8(3),153-156. Full Article

ANTIULCER

Cavalcanti, A. M., Baggio, C. H., Freitas, C. S., Rieck, L., De fSousa, R. S., Da Silva-Santos, J. E., ... & Marques, M. C. A. (2006). Safety and antiulcer efficacy studies of Achillea millefolium L. after chronic treatment in Wistar rats. Journal of ethnopharmacology, 107(2), 277-284. Full Article

ANTISPASMODIC

Moradi, M., Rafieian-Koupaei, M., Imani-Rastabi, R., Nasiri, J., Shahrani, M., Rabiei, Z., & Alibabaei, Z. (2013). Antispasmodic effects of yarrow (Achillea millefolium L.) extract in the isolated ileum of rat. African Journal of Traditional, Complementary and Alternative Medicines, 10(6), 499-503. Full Article

ANTITUMOR

Tozyo, T., YOSHIMURA, Y., SAKURAI, K., UCHIDA, N., TAKEDA, Y., NAKAI, H., & ISHII, H. (1994). Novel antitumor sesquiterpenoids in Achillea millefolium. Chemical and Pharmaceutical Bulletin, 42(5), 1096-1100. Full Article

ANTI-LIMNATIS

Bahmani, M., Abdi, F., Adineh, A., Hassanzadazar, H., Eghbali, B., Gholami-Ahangaran, M., & Rafieian-Kopaei, M. (2014). The Anti-Leech Effect of Ethanolic Extract of Achillea Millefolium L. Compared to Levamisole and Niclosamide on Limnatis Nilotica. Studia Universitatis" Vasile Goldis" Arad. Seria Stiintele Vietii (Life Sciences Series), 24(3), 293. Full Article

ANXIOLYTIC

Baretta, I. P., Felizardo, R. A., Bimbato, V. F., dos Santos, M. G. J., Kassuya, C. A. L., Junior, A. G., ... & Andreatini, R. (2012). Anxiolytic-like effects of acute and chronic treatment with Achillea millefolium L. extract. Journal of Ethnopharmacology, 140(1), 46-54. Full Article

HEPATOPROTECTIVE

Yaeesh, S., Jamal, Q., Khan, A. U., & Gilani, A. H. (2006). Studies on hepatoprotective, antispasmodic and calcium antagonist activities of the aqueous‐methanol extract of Achillea millefolium. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 20(7), 546-551. Full Article

GIT HEALTH

Yakhkeshi, S., Rahimi, S., & Hemati Matin, H. R. (2012). Effects of yarrow (Achillea millefolium L.), antibiotic and probiotic on performance, immune response, serum lipids and microbial population of broilers. Journal of Agricultural Science and Technology, 14(4), 799-810. Full Article

SPASMOLYTIC

Lemmens-Gruber, R., Marchart, E., Rawnduzi, P., Engel, N., Benedek, B., & Kopp, B. (2006). Investigation of the spasmolytic activity of the flavonoid fraction of Achillea millefolium sl on isolated guinea-pig ilea. Arzneimittelforschung, 56(08), 582-588. Full Article

WOUND HEALING

Nirmala, S., & Karthiyayini, T. (2011). Wound healing activity on the leaves of Achillea millefolium L. by excision, incision, and dead space model on adult wistar albino rats. Int Res J Pharm, 2(3), 240-245. Full Article

Hemmati, A. A., Arzi, A., & Amin, M. (2002). Effect of Achillea millefolium extract in wound healing of rabbit. Journal of Natural Remedies, 2(2), 164-167. Full Article

VASOPROTECTIVE

Dall’Acqua, S., Bolego, C., Cignarella, A., Gaion, R. M., & Innocenti, G. (2011). Vasoprotective activity of standardized Achillea millefolium extract. Phytomedicine, 18(12), 1031-1036. Full Article

VARIOUS USES

Četojević-Simin, D. D., Ranitović, A. S., Cvetković, D. D., Markov, S. L., Vinčić, M. N., & Đilas, S. M. (2017). Bioactivity of blackberry (Rubus fruticosus L.) pomace: Polyphenol content, radical scavenging, antimicrobial and antitumor activity. Acta Periodica Technologica, 2017(48), 63-76. Full Article

Verma, R., Gangrade, T., Punasiya, R., & Ghulaxe, C. (2014). Rubus fruticosus (blackberry) use as an herbal medicine. Pharmacognosy reviews, 8(16), 101. Full Article

Zia-Ul-Haq, M., Riaz, M., De Feo, V., Jaafar, H. Z., & Moga, M. (2014). Rubus fruticosus L.: constituents, biological activities and health related uses. Molecules, 19(8), 10998-11029. Full Article

Khan, A. U., & Gilani, A. H. (2011). Blood pressure lowering, cardiovascular inhibitory and bronchodilatory actions of Achillea millefolium. Phytotherapy Research, 25(4), 577-583. Full Article

Cowden Support Program for Lyme: Observational Study – Dublin, Ireland – June, 2012 Armin Schwarzbach, MD PhD Full Video

"I've used this with success to help calm eczema flare-ups during my metal cleanse; plus, my cat's chin acne.  I've also combined it with NutraMedix Houttuynia for nose redness and pain. I think it is great!" -B.LGreat product for Lyme disease like all Cowden products.  This is by far the best protocol to address Lyme and the most cost effective too.  Strong stuff without side effects.  Until now there is no better option available to keep Lyme in remission."-F.S.

30 drops twice daily at least 30 minutes before meals (start with 1 drop in 4 oz. of water adding a drop with each dose as tolerated).

An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Mora did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary. Full Article