FOR RESOLVING BLOOD SUGAR REGULATION ISSUES; FOR USE AS A SWEETENER AND ANTIBACTERIAL

General Description

Stevia is an extract from Stevia rebaudiana, having up to 300 times the sweetness of sugar. Stevia has garnered attention with the rise in demand for low-carbohydrate, low-sugar food alternatives. Nutramedix Stevia was identified as "Stevia A" in a study published in 2015 where it was shown to be more effective than doxycycline in eliminating Borreliaburgdorferi, in all morphologic forms. It also demonstrated a significant effect in eliminating B.burgdorferi biofilms which were exacerbated when using doxycycline.

Some Reported Medicinal Properties

ANTI-ACNE

ANTI-BACTERIAL

ANTI-CANDIDIASIS

ANTI-DANDRUFF

ANTI-DERMATITIS

ANTI-DIABETES

ANTI-CYSTITIS

ANTI-DYSPEPTIC

ANTI-GINGIVITIS

ANTI-HEARTBURN

ANTI-INFLAMMATORY BOWEL DISEASE

ANTI-NEPHROPATHY

ANTI-OBESITY

ANTI-OSTEOPOROTIC

ANTIOXIDANT

ANTI-RASH

ANTISEPTIC

ANTI-TOOTH DECAY

ANTI-TUMOR

DIURETIC

HYPOGLYCEMIC

HYPOTENSIVE

NATRIURETIC

PRO-ENERGY

Reasearch On Nutramedix Product

IN VITRO – LYME DISEASE

Priyanka A.S. Theophilus M.S., Eva Sapi Ph.D. (2013). In Vitro Effect of Peruvian Antimicrobial Agents on Borrelia burgdorferi Full Article

IN VIVO – ACUTE ORAL TOXICITY TESTS

An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Stevia did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary. Full Article

LYME

Theophilus, P. A. S., Victoria, M. J., Socarras, K. M., Filush, K. R., Gupta, K., Luecke, D. F., & Sapi, E. (2015). Effectiveness of Stevia rebaudiana whole leaf extract against the various morphological forms of Borrelia burgdorferi in vitro. European Journal of Microbiology and Immunology, 5(4), 268-280. Full Article

Medical Conditions [peer-reviewed journals]

HUMAN ROTAVIRUS (HRV)

Takahashi, K., Matsuda, M., Ohashi, K., Taniguchi, K., Nakagomi, O., Abe, Y., ... & Shigeta, S. (2001). Analysis of anti-rotavirus activity of extract from Stevia rebaudiana. Antiviral research, 49(1), 15-24. Full Article

DIABETES

Ahmad, U., & Ahmad,R. S. (2018). Anti diabetic property of aqueous extract of Stevia rebaudiana Bertoni leaves in Streptozotocin-induced diabetes in albino rats. BMC complementary and alternative medicine, 18(1),179. Full Article

Carrera-Lanestosa, A.,Moguel-Ordóñez, Y., & Segura-Campos, M. (2017). Stevia rebaudiana Bertoni: a natural alternative for treating diseases associated with metabolic syndrome. Journal of medicinal food, 20(10), 933-943. Full Article

AbdElwahab, A. H.,Yousuf, A. F., Ramadan, B. K., & Elimam, H. (2017). Comparative Effects of Stevia rebaudiana and Aspartame on hepato-renal function of diabetic rats: Biochemical and Histological Approaches. Journal of Applied Pharmaceutical Science Vol, 7(08), 034-042. Full Article

Patil, A., Nirmal, S.,Pattan, S., Tambe, V., & Tare, M. (2012). Antidiabetic effect of polyherbal combinations in STZ induced diabetes involve inhibition of α-amylase and α-glucosidase with amelioration of lipid profile. Phytopharmacology, 2(1), 46-57. Full Article

Pallarés, Á., Carrasco,G., Nava, Y., Pallarés, O., Pérez, I., Rifá, R., & Rodríguez, M. (2015). Effectiveness and safety of Stevia rebaudiana dried leaves as an adjuvant in the short-term treatment of type 2 diabetes: A randomized, controlled, cross-over and double-blinded trial. JMed Plant Herbal Ther Res, 3, 16-26. Full Article

Ruiz-Ruiz, J. C.,Moguel-Ordoñez, Y. B., Matus-Basto, A. J., & Segura-Campos, M. R. (2015). Antidiabetic and antioxidant activity of Stevia rebaudiana extracts (Var. Morita) and their incorporation into a potential functional bread. Journal of food science and technology, 52(12),7894-7903. Full Article

Parimalavalli, R.,& Radhaisri, S. (2011). Glycaemic index of stevia product and its efficacy on blood glucose level in type 2 diabetes. Indian Journal of Science and Technology, 4(3), 318-321. Full Article

Sharma, R., Yadav, R.,& Manivannan, E. (2012). Study of effect of Stevia rebaudiana bertoni on oxidative stress in type-2 diabetic rat models. Biomedicine & Aging Pathology, 2(3), 126-131. Full Article

Maki, K. C., Curry, L.L., Reeves, M. S., Toth, P. D., McKenney, J. M., Farmer, M. V., ... & Carakostas, M. C. (2008). Chronic consumption of rebaudioside A, a steviol glycoside, in men and women with type 2 diabetes mellitus.Food and Chemical Toxicology, 46(7), S47-S53. Full Article

Sumon, M. H., Mostofa,M., Jahan, M. S., Kayesh, M. E. H., & Haque, M. A. (2008). Comparative efficacy of powdered form of stevia (Stevia rebaudiana Bertoni) leaves and glimepiride in induced diabetic rats. Bangl. J. Vet. Med, 6(2), 211-215. Full Article

Dyrskog, S. E. U.,Jeppesen, P. B., Colombo, M., Abudula, R., & Hermansen, K. (2005). Preventive effects of a soy-based diet supplemented with stevioside on the development of the metabolic syndrome and type 2 diabetes in Zucker diabetic fatty rats. Metabolism, 54(9),1181-1188. Full Article

Giri, A., Rao, H. R.,& Ramesh, V. (2014). Effect of partial replacement of sugar with stevia on the quality of kulfi. Journal of food science and technology, 51(8), 1612-1616. Full Article

Ozbayer, C., Kurt, H.,Kalender, S., Ozden, H., Gunes, H. V., Basaran, A., ... & Degirmenci, I.(2011). Effects of Stevia rebaudiana (Bertoni) extract and N-nitro-L-arginine on renal function and ultrastructure of kidney cells in experimental type 2 Diabetes. Journal of medicinal food, 14(10), 1215-1222. Full Article

Anton, S. D., Martin,C. K., Han, H., Coulon, S., Cefalu, W. T., Geiselman, P., & Williamson, D.A. (2010). Effects of stevia, aspartame, and sucrose on food intake, satiety, and postprandial glucose and insulin levels. Appetite, 55(1), 37-43. Full Article

Assaei, R., Mokarram,P., Dastghaib, S., Darbandi, S., Darbandi, M., Zal, F., ... & Omrani, G. H.R. (2016). Hypoglycemic effect of aquatic extract of stevia in pancreas of diabetic rats: PPARγ-dependent regulation or antioxidant potential. Avicenna journal of medical biotechnology, 8(2), 65. Full Article

Gupta, E., Purwar, S.,Sundaram, S., & Rai, G. K. (2013). Nutritional and therapeutic values of Stevia rebaudiana: A review. Journal of Medicinal Plants Research, 7(46), 3343-3353. Full Article

Shivanna, N., Naika,M., Khanum, F., & Kaul, V. K. (2013). Antioxidant, anti-diabetic and renal protective properties of Stevia rebaudiana. Journal of Diabetes and its Complications, 27(2), 103-113. Full Article

Kujur, R. S., Singh,V., Ram, M., Yadava, H. N., Singh, K. K., Kumari, S., & Roy, B. K. (2010). Antidiabetic activity and phytochemical screening of crude extract of Stevia rebaudiana in alloxan-induced diabetic rats.Pharmacognosy research, 2(4), 258. Full Article

Ritu, M., & Nandini, J. (2016). Nutritional composition of Stevia rebaudiana, a sweet herb, and its hypoglycaemic and hypolipidaemic effect on patients with non‐insulin dependent diabetes mellitus. Journal of the Science of Food and Agriculture, 96(12), 4231-4234. Full Article

Laribi, B., Rouatbi,N., Kouki, K., & Bettaieb, T. (2012). In vitro propagation of Stevia rebaudiana (Bert.)-A non-caloric sweetener and antidiabetic medicinal plant. Int. J. Med. Arom. Plants, 2(2), 333-339. Full Article

Mohd-Radzman, N. H.,Ismail, W. I. W., Adam, Z., Jaapar, S. S., & Adam, A. (2013). Potential roles of Stevia rebaudiana Bertoni in abrogating insulin resistance and diabetes: a review. Evidence-Based Complementary and Alternative Medicine, 2013. Full Article

Jeppesen, P. B.,Gregersen, S., Poulsen, C. R., & Hermansen, K. (2000). Stevioside acts directly on pancreatic β cells to secrete insulin: Actions independent of cyclic adenosine monophosphate and adenosine triphosphate—sensitive K+-channel activity. Metabolism, 49(2), 208-214. Full Article

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Medicinal Properties [peer-reviewed journals]

ANTIBACTERIAL

Fazal, H. I. N. A., Ahmad, N., Ullah, I., Inayat, H., Khan, L., & Abbasi, B. H. (2011). Antibacterial potential in Parthenium hysterophorus, Stevia rebaudiana and Ginkgo biloba. Pak. J. Bot, 43(2), 1307-1313. Full Article

ANTIDIABETIC

Kujur, R. S., Singh, V., Ram, M., Yadava, H. N., Singh, K. K., Kumari, S., & Roy, B. K. (2010). Antidiabetic activity and phytochemical screening of crude extract of Stevia rebaudiana in alloxan-induced diabetic rats.Pharmacognosy research, 2(4), 258. Full Article

ANTIMICROBIAL

Ghosh, S., Subudhi, E., & Nayak, S. (2008). Antimicrobial assay of Stevia rebaudiana Bertoni leaf extracts against 10 pathogens. Int J Integr Biol, 2(1), 1-5. Full Article

Jayaraman, S., Manoharan, M. S., & Illanchezian, S. (2008). In-vitro antimicrobial and antitumor activities of Stevia rebaudiana (Asteraceae) leaf extracts. Tropical Journal of Pharmaceutical Research, 7(4), 1143-1149. Full Article

Debnath, M. (2007). Clonal propagation and antimicrobial activity of an endemic medicinal plant Stevia rebaudiana. Journal of medicinal plants research, 2(2), 045-051. Full Article

Tadhani, M. B., & Subhash, R. (2006). In vitro antimicrobial activity of Stevia rebaudiana Bertoni leaves. Tropical Journal of Pharmaceutical Research, 5(1), 557-560. Full Article

ANTIOXIDANT

Barba, F. J., Criado, M. N., Belda-Galbis, C. M., Esteve, M. J., & Rodrigo, D. (2014). Stevia rebaudiana Bertoni as a natural antioxidant/antimicrobial for high pressure processed fruit extract: Processing parameter optimization. Food Chemistry, 148, 261-267. Full Article

Shukla, S., Mehta, A., Mehta, P., & Bajpai, V. K. (2012). Antioxidant ability and total phenolic content of aqueous leaf extract of Stevia rebaudiana Bert. Experimental and Toxicologic Pathology, 64(7-8), 807-811. Full Article

Kim, I. S., Yang, M., Lee, O. H., & Kang, S. N. (2011). The antioxidant activity and the bioactive compound content of Stevia rebaudiana water extracts. LWT-Food Science and Technology, 44(5), 1328-1332. Full Article

Shukla, S., Mehta, A., Bajpai, V. K., & Shukla, S. (2009). In vitro antioxidant activity and total phenolic content of ethanolic leaf extract of Stevia rebaudiana Bert. Food and Chemical Toxicology, 47(9), 2338-2343 Full Article

Tadhani, M. B., Patel, V. H., & Subhash, R. (2007). In vitro antioxidant activities of Stevia rebaudiana leaves and callus. Journal of food composition and Analysis, 20(3-4), 323-329. Full Article

Conference Presentations

Cowden Support Program for Lyme: Observational Study – Dublin, Ireland – June, 2012 Armin Schwarzbach, MD PhD Full Video

Patient Reports

“Has a great sweet taste, I use this for my Lyme disease, and I did herx on it at first, so I had to back off a little, but it works fine, and since its best for me to stay away from sugar, it’s a great sweetener, i put in my water with a squeeze of lemon. love it.” - A.S

“I have to take a few antimicrobials for a bacterial infection, and this stevia definitely improves the taste!” – K.L

“Curbs sugar craving. Excellent for anyone with Lyme disease or a that's looking for a good quality extract.” – M.L

"I've been addicted to sugar since I was 5. My doctor told me that I was going into pre-diabetes and that I better make a change. He told me about NutraMedix Stevia – that it wasn't a fractured, processed version of the Stevia plant. He said that it came from the plant as a whole food and that's been my goal ever since – to get healthy by eating whole foods and no sugar. I'm proud to say I've lost 50 pounds and I no longer crave sugar. This Stevia is really good." -R.M.

Dosage Information

Add 3 or more drops as desired to food or beverages. As an antimicrobial, use 30 drops twice daily. Nutramedix Stevia contains no added sugars.

Safety Information

An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Stevia did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary. Full Article

Nutramedix, STEVIA - Sweet Hearb Nutramedix, STEVIA - Sweet Hearb