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SUPPORT RESTFUL SLEEP - Chamomile has long been used for its potential sleep supportive properties, and may promote feelings of relaxation.
Babuna is an extract produced from the flower of Matricaria recutita, commonly known as chamomile. Azulene, one of the active natural substances found in Babuna, has been shown to inhibit histamine release and to regulate the effect of serotonin. Serotonin is a multi-role neurotransmitter that the body produces in the brain and other nervous tissue. One of the important functions of serotonin is to slow down nerve traffic and induce normal sleep. The inability to sleep is often caused by a serotonin deficiency. Via the proprietary process used to produce Babuna, this remedy has been designed to improve serotonin function and therefore improve sleep.
PROPRIETARY WHOLE HERB EXTRACTION PROCESS - Highly bioavailable liquid for improved absorption. Nutramedix’s unique enhancement process optimizes the whole herb for a more powerful broad-spectrum extract.
FROM NATURE - Our products are sourced from nature’s richest botanical resources, primarily Peru and the Amazon Rainforest.
FEEL THE DIFFERENCE - Put 15 drops in 4 oz. of water and wait one minute before drinking. Take at bedtime or as directed by your physician. Repeat during the night as needed. Do not use if pregnant or nursing. Shake well before each use.
Keefe, J. R., Guo, W., Li, Q. S., Amsterdam, J. D., & Mao, J.J. (2018). An exploratory study ofsalivary cortisol changes during chamomile extract therapy of moderate tosevere generalized anxiety disorder. Journal of Psychiatric Research, 96,189-195. Full Article
Amsterdam, J. D., Li, Y., Soeller, I., Rockwell, K., Mao, J. J.,& Shults, J. (2009). A randomized,double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile)extract therapy of generalized anxiety disorder. Journal of Clinical Psychopharmacology, 29(4), 378. Full Article
Srivastava, J. K., & Gupta, S.(2007). Antiproliferative and apoptoticeffects of chamomile extract in various human cancer cells. Journal of Agricultural and Food Chemistry, 55(23), 9470-9478. Full Article
Emam, M. A. (2012). Comparative evaluation of antidiabeticactivity of Rosmarinus officinalis L. and Chamomile recutita in streptozotocininduced diabetic rats. Agric. Biol. JN Am, 3(6), 247-252. Full Article
Gomes, V. T. S., Nonato Silva Gomes,R., Gomes, M. S., Joaquim, W. M., Lago, E. C., & Nicolau, R. A. (2018). Effects of Matricaria Recutita (L.) in theTreatment of Oral Mucositis. The Scientific World Journal, 2018. Full Article
Fidler, P., Loprinzi, C. L.,O'Fallon, J. R., Leitch, J. M., Lee, J. K., Hayes, D. L., ... & Michalak,J. C. (1996). Prospective evaluation ofa chamomile mouthwash for prevention of 5‐FU‐induced oral mucositis. Cancer: Interdisciplinary International Journal of the American Cancer Society, 77(3),522-525. Full Article
Asadi-Shahmirzadi, A., Mozaffari, S.,Sanei, Y., Baeeri, M., Hajiaghaee, R., Monsef-Esfahani, H. R., & Abdollahi,M. (2012). Benefit of Aloe vera and Matricaria recutita mixture in rat irritable bowel syndrome: Combination ofantioxidant and spasmolytic effects. Chinese Journal of Integrativemedicine, 1-9. Full Article
Srivastava, J. K., Shankar, E., &Gupta, S. (2010). Chamomile: a herbalmedicine of the past with a bright future. Molecular Medicine Reports, 3(6), 895-901. Full Article
Gardiner, P. (2007). Complementary, holistic, and integrativemedicine: chamomile. Pediatrics in Review, 28(4), e16. Full Article
Chandrashekhar, V. M., Halagali, K. S., Nidavani, R. B., Shalavadi, M. H., Biradar, B. S., Biswas, D., & Muchchandi, I. S. (2011). Anti-allergic activity of German chamomile (Matricaria recutita L.) in mast cell mediated allergy model. Journal of Ethnopharmacology, 137(1), 336-340. Full Article
M Moricz, A., Szarka, S., G Ott, P., B Hethelyi, E., Szoke, E., & Tyihak, E. (2012). Separation and identification of antibacterial chamomile components using OPLC, bioautography and GC-MS. Medicinal Chemistry, 8(1), 85-94. Full Article
Amsterdam, J. D., Shults, J., Soeller, I., Mao, J. J., Rockwell, K., & Newberg, A. B. (2012). Chamomile (matricaria recutita) may have antidepressant activity in anxious depressed humans-an exploratory study. Alternative Therapies in Health and Medicine, 18(5), 44. Full Article
Jamalian, A., Shams-Ghahfarokhi, M., Jaimand, K., Pashootan, N., Amani, A., & Razzaghi-Abyaneh, M. (2012). Chemical composition and antifungal activity of Matricaria recutita flower essential oil against medically important dermatophytes and soil-borne pathogens. Journal de Mycologie Médicale/Journal of Medical Mycology, 22(4), 308-315. Full Article
Begum, N. (2017). In vitro investigation of anti-inflammatory and COX-2 inhibitory potential of flower extracts of Matricaria recutita. International Journal of Green Pharmacy (IJGP), 11(02). Full Article
Bhaskaran, N., Shukla, S., Srivastava, J. K., & Gupta, S. (2010). Chamomile: an anti-inflammatory agent inhibits inducible nitric oxide synthase expression by blocking RelA/p65 activity. International Journal of Molecular Medicine, 26(6), 935-940. Full Article
Srivastava, J. K., Pandey, M., & Gupta, S. (2009). Chamomile, a novel and selective COX-2 inhibitor with anti-inflammatory activity. Life Sciences, 85(19-20), 663-669. Full Article
Heidari, M. R., Dadollahi, Z., Mehrabani, M., Mehrabi, H., Pourzadeh‐Hosseini, M., Behravan, E., & Etemad, L. (2009). Study of antiseizure effects of Matricaria recutita extract in mice. Annals of the New York Academy of Sciences, 1171(1), 300-304. Full Article
Göger, G., Demirci, B., Ilgın, S., & Demirci, F. (2018). Antimicrobial and toxicity profiles evaluation of the Chamomile (Matricaria recutita L.) essential oil combination with standard antimicrobial agents. Industrial Crops and Products, 120, 279-285. Full Article
Abd El Raheim, M., Alam, A., Nour, Y. S., & Radwan, A. M. (2016). Evaluation of Antimicrobial and Antioxidant activities of Matricaria recutita, Ricinus communis and Zygophyllum coccineum Extracts. Bull. Env. Pharmacol. Life Sci, 5, 30-33. Full Article
Kazemi, M. (2015). Chemical composition and antimicrobial activity of essential oil of Matricaria recutita.International Journal of Food Properties, 18(8), 1784-1792. Full Article
Hwang, S. H., Wang, Z., Quispe, G., Yanymee, N., Lim, S. S., & Yu, J. M. (2018). Evaluation of Aldose Reductase, Protein Glycation, and Antioxidant Inhibitory Activities of Bioactive Flavonoids in Matricaria recutita L. and Their Structure-Activity Relationship. Journal of Diabetes Research, 2018. Full Article
Hajaji, S., Sifaoui, I., López-Arencibia, A., Reyes-Batlle, M., Jiménez, I. A., Bazzocchi, I. L., ... & Akkari, H. (2017). Correlation of radical-scavenging capacity and amoebicidal activity of Matricaria recutita L.(Asteraceae).Experimental parasitology, 183, 212-217. Full Article
Hashemi, S. M. B., Brewer, M. S., Safari, J., Nowroozi, M., Abadi Sherahi, M. H., Sadeghi, B., & Ghafoori, M. (2016). Antioxidant activity, reaction mechanisms, and kinetics of Matricaria recutita extract in commercial blended oil oxidation. International Journal of Food Properties, 19(2), 257-271. Full Article
Sebai, H., Jabri, M. A., Souli, A., Hosni, K., Rtibi, K., Tebourbi, O., ... & Sakly, M. (2015). Chemical composition, antioxidant properties and hepatoprotective effects of chamomile (Matricaria recutita L.) decoction extract against alcohol-induced oxidative stress in rat. General Physiology and Biophysics, 34(3), 263-275. Full Article
Sebai, H., Jabri, M. A., Souli, A., Rtibi, K., Selmi, S., Tebourbi, O., ... & Sakly, M. (2014). Antidiarrheal and antioxidant activities of chamomile (Matricaria recutita L.) decoction extract in rats. Journal of Ethnopharmacology, 152(2), 327-332. Full Article
Pereira, R. P., Fachinetto, R., de Souza Prestes, A., Puntel, R. L., Da Silva, G. N. S., Heinzmann, B. M., ... & Morsch, V. M. (2009). Antioxidant effects of different extracts from Melissa officinalis, Matricaria recutita and Cymbopogon citratus. Neurochemical Research, 34(5), 973-983. Full Article
Kobayashi, Y., Takahashi, R., & Ogino, F. (2005). Antipruritic effect of the single oral administration of German chamomile flower extract and its combined effect with antiallergic agents in ddY mice. Journal of Ethnopharmacology, 101(1-3), 308-312. Full Article
Kobayashi, Y., Nakano, Y., Inayama, K., Sakai, A., & Kamiya, T. (2003). Dietary intake of the flower extracts of German chamomile (Matricaria recutita L.) inhibited compound 48/80-induced itch-scratch responses in mice.Phytomedicine, 10(8), 657-664. Full Article
Koch, C., Reichling, J., Kehm, R., Sharaf, M. M., Zentgraf, H., Schneele, J., & Schnitzler, P. (2008). Efficacy of anise oil, dwarf‐pine oil and chamomile oil against thymidine‐kinase‐positive and thymidine‐kinase‐negative herpesviruses. Journal of Pharmacy and Pharmacology, 60(11), 1545-1550. Full Article
Viola, H., Wasowski, C., De Stein, M. L., Wolfman, C., Silveira, R., Dajas, F., ... & Paladini, A. C. (1995). Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects. Planta Medica, 61(03), 213-216. Full Abstract
Hajaji, S., Sifaoui, I., López-Arencibia, A., Reyes-Batlle, M., Jiménez, I. A., Bazzocchi, I. L., ... & Piñero, J. E. (2018). Leishmanicidal activity of α-bisabolol from Tunisian chamomile essential oil. Parasitology Research, 1-13. Full Article
Ranpariya, V. L., Parmar, S. K., Sheth, N. R., & Chandrashekhar, V. M. (2011). Neuroprotective activity of Matricaria recutita against fluoride-induced stress in rats. Pharmaceutical Biology, 49(7), 696-701. Full Article
Chandrashekhar, V. M., Ranpariya, V. L., Ganapaty, S., Parashar, A., & Muchandi, A. A. (2010). Neuroprotective activity of Matricaria recutita Linn against global model of ischemia in rats. Journal of Ethnopharmacology, 127(3), 645-651. Full Article
Zargaran, A., Borhani-Haghighi, A., Salehi-Marzijarani, M., Faridi, P., Daneshamouz, S., Azadi, A., ... & Mohagheghzadeh, A. (2018). Evaluation of the effect of topical chamomile (Matricaria chamomilla L.) oleogel as pain relief in migraine without aura: a randomized, double-blind, placebo-controlled, crossover study. Neurological Sciences, 1-9. Full Article
Sándor, Z., Mottaghipisheh, J., Veres, K., Hohmann, J., Bencsik, T., Horváth, A., ... & Csupor, D. (2018). Evidence supports tradition: the in vitro effects of Roman Chamomile on smooth muscles. Frontiers in Pharmacology, 9, 323. Full Article
Petronilho, S., Maraschin, M., Coimbra, M. A., & Rocha, S. M. (2012). In vitro and in vivo studies of natural products: A challenge for their valuation. The case study of chamomile (Matricaria recutita L.). Industrial Crops and Products, 40, 1-12. Full Article
“Seems to help with sleep. Very convenient. I use it sublingually sometimes if I wake up too early” – C.T
“I really didn't expect this to work very well and was very pleased to find that it's really very effective and I only take three drops per night.” – M.J
"I use this every night and it works great for me, I don't feel that sleeping med drowsiness in the morning either."-R.I.
"Absolutely fantastic! Me and my teenage daughter couldn't cope without it. Closes off any 'brainwaves' and allows you to go to sleep within 20 minutes." -E.H.
15 Drops in 4 oz. of water at bedtime. Repeat during the night as needed. Can also be used at a dose of 10-15 drops during the day as needed for anxiety.
An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Babuna did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary. Full Article
OVER 20 YEARS OF NUTRACEUTICAL INNOVATION - Founded in 1993, Nutramedix supplies highly bioavailable nutritional supplements to health care professionals and consumers. A majority of Nutramedix profits are donated to charitable organizations.