BABUNA - Chamomile Sleep Support

SUPPORT RESTFUL SLEEP - Chamomile has long been used for its potential sleep supportive properties, and may promote feelings of relaxation. General Description Babuna is an extract produced from the flower of...


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SUPPORT RESTFUL SLEEP - Chamomile has long been used for its potential sleep supportive properties, and may promote feelings of relaxation.

General Description

Babuna is an extract produced from the flower of Matricaria recutita, commonly known as chamomile. Azulene, one of the active natural substances found in Babuna, has been shown to inhibit histamine release and to regulate the effect of serotonin. Serotonin is a multi-role neurotransmitter that the body produces in the brain and other nervous tissue. One of the important functions of serotonin is to slow down nerve traffic and induce normal sleep. The inability to sleep is often caused by a serotonin deficiency. Via the proprietary process used to produce Babuna, this remedy has been designed to improve serotonin function and therefore improve sleep.

Some Reported Medicinal Properties






















PROPRIETARY WHOLE HERB EXTRACTION PROCESS - Highly bioavailable liquid for improved absorption. Nutramedix’s unique enhancement process optimizes the whole herb for a more powerful broad-spectrum extract.

FROM NATURE - Our products are sourced from nature’s richest botanical resources, primarily Peru and the Amazon Rainforest.

FEEL THE DIFFERENCE - Put 15 drops in 4 oz. of water and wait one minute before drinking. Take at bedtime or as directed by your physician. Repeat during the night as needed. Do not use if pregnant or nursing. Shake well before each use.

Medical Conditions [peer-reviewed journals]


Keefe, J. R., Guo, W., Li, Q. S., Amsterdam, J. D., & Mao, J.J. (2018). An exploratory study ofsalivary cortisol changes during chamomile extract therapy of moderate tosevere generalized anxiety disorder. Journal of Psychiatric Research, 96,189-195. Full Article

Amsterdam, J. D., Li, Y., Soeller, I., Rockwell, K., Mao, J. J.,& Shults, J. (2009). A randomized,double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile)extract therapy of generalized anxiety disorder. Journal of Clinical Psychopharmacology, 29(4), 378. Full Article


Srivastava, J. K., & Gupta, S.(2007). Antiproliferative and apoptoticeffects of chamomile extract in various human cancer cells. Journal of Agricultural and Food Chemistry, 55(23), 9470-9478. Full Article


Emam, M. A. (2012). Comparative evaluation of antidiabeticactivity of Rosmarinus officinalis L. and Chamomile recutita in streptozotocininduced diabetic rats. Agric. Biol. JN Am, 3(6), 247-252. Full Article


Gomes, V. T. S., Nonato Silva Gomes,R., Gomes, M. S., Joaquim, W. M., Lago, E. C., & Nicolau, R. A. (2018). Effects of Matricaria Recutita (L.) in theTreatment of Oral Mucositis. The Scientific World Journal, 2018. Full Article

Fidler, P., Loprinzi, C. L.,O'Fallon, J. R., Leitch, J. M., Lee, J. K., Hayes, D. L., ... & Michalak,J. C. (1996). Prospective evaluation ofa chamomile mouthwash for prevention of 5‐FU‐induced oral mucositis. Cancer: Interdisciplinary International Journal of the American Cancer Society, 77(3),522-525. Full Article


Asadi-Shahmirzadi, A., Mozaffari, S.,Sanei, Y., Baeeri, M., Hajiaghaee, R., Monsef-Esfahani, H. R., & Abdollahi,M. (2012). Benefit of Aloe vera and Matricaria recutita mixture in rat irritable bowel syndrome: Combination ofantioxidant and spasmolytic effects. Chinese Journal of Integrativemedicine, 1-9. Full Article


Srivastava, J. K., Shankar, E., &Gupta, S. (2010). Chamomile: a herbalmedicine of the past with a bright future. Molecular Medicine Reports, 3(6), 895-901. Full Article

Gardiner, P. (2007). Complementary, holistic, and integrativemedicine: chamomile. Pediatrics in Review, 28(4), e16. Full Article

Medicinal Properties [peer-reviewed journals]


Chandrashekhar, V. M., Halagali, K. S., Nidavani, R. B., Shalavadi, M. H., Biradar, B. S., Biswas, D., & Muchchandi, I. S. (2011). Anti-allergic activity of German chamomile (Matricaria recutita L.) in mast cell mediated allergy model. Journal of Ethnopharmacology, 137(1), 336-340. Full Article


M Moricz, A., Szarka, S., G Ott, P., B Hethelyi, E., Szoke, E., & Tyihak, E. (2012). Separation and identification of antibacterial chamomile components using OPLC, bioautography and GC-MS. Medicinal Chemistry, 8(1), 85-94. Full Article


Amsterdam, J. D., Shults, J., Soeller, I., Mao, J. J., Rockwell, K., & Newberg, A. B. (2012). Chamomile (matricaria recutita) may have antidepressant activity in anxious depressed humans-an exploratory study. Alternative Therapies in Health and Medicine, 18(5), 44. Full Article


Jamalian, A., Shams-Ghahfarokhi, M., Jaimand, K., Pashootan, N., Amani, A., & Razzaghi-Abyaneh, M. (2012). Chemical composition and antifungal activity of Matricaria recutita flower essential oil against medically important dermatophytes and soil-borne pathogens. Journal de Mycologie Médicale/Journal of Medical Mycology, 22(4), 308-315. Full Article


Begum, N. (2017). In vitro investigation of anti-inflammatory and COX-2 inhibitory potential of flower extracts of Matricaria recutita. International Journal of Green Pharmacy (IJGP), 11(02). Full Article

Bhaskaran, N., Shukla, S., Srivastava, J. K., & Gupta, S. (2010). Chamomile: an anti-inflammatory agent inhibits inducible nitric oxide synthase expression by blocking RelA/p65 activity. International Journal of Molecular Medicine, 26(6), 935-940. Full Article

Srivastava, J. K., Pandey, M., & Gupta, S. (2009). Chamomile, a novel and selective COX-2 inhibitor with anti-inflammatory activity. Life Sciences, 85(19-20), 663-669. Full Article


Heidari, M. R., Dadollahi, Z., Mehrabani, M., Mehrabi, H., Pourzadeh‐Hosseini, M., Behravan, E., & Etemad, L. (2009). Study of antiseizure effects of Matricaria recutita extract in mice. Annals of the New York Academy of Sciences, 1171(1), 300-304. Full Article


Göger, G., Demirci, B., Ilgın, S., & Demirci, F. (2018). Antimicrobial and toxicity profiles evaluation of the Chamomile (Matricaria recutita L.) essential oil combination with standard antimicrobial agents. Industrial Crops and Products, 120, 279-285. Full Article

Abd El Raheim, M., Alam, A., Nour, Y. S., & Radwan, A. M. (2016). Evaluation of Antimicrobial and Antioxidant activities of Matricaria recutita, Ricinus communis and Zygophyllum coccineum Extracts. Bull. Env. Pharmacol. Life Sci, 5, 30-33. Full Article

Kazemi, M. (2015). Chemical composition and antimicrobial activity of essential oil of Matricaria recutita.International Journal of Food Properties, 18(8), 1784-1792. Full Article


Hwang, S. H., Wang, Z., Quispe, G., Yanymee, N., Lim, S. S., & Yu, J. M. (2018). Evaluation of Aldose Reductase, Protein Glycation, and Antioxidant Inhibitory Activities of Bioactive Flavonoids in Matricaria recutita L. and Their Structure-Activity Relationship. Journal of Diabetes Research, 2018. Full Article

Hajaji, S., Sifaoui, I., López-Arencibia, A., Reyes-Batlle, M., Jiménez, I. A., Bazzocchi, I. L., ... & Akkari, H. (2017). Correlation of radical-scavenging capacity and amoebicidal activity of Matricaria recutita L.(Asteraceae).Experimental parasitology, 183, 212-217. Full Article

Hashemi, S. M. B., Brewer, M. S., Safari, J., Nowroozi, M., Abadi Sherahi, M. H., Sadeghi, B., & Ghafoori, M. (2016). Antioxidant activity, reaction mechanisms, and kinetics of Matricaria recutita extract in commercial blended oil oxidation. International Journal of Food Properties, 19(2), 257-271. Full Article

Sebai, H., Jabri, M. A., Souli, A., Hosni, K., Rtibi, K., Tebourbi, O., ... & Sakly, M. (2015). Chemical composition, antioxidant properties and hepatoprotective effects of chamomile (Matricaria recutita L.) decoction extract against alcohol-induced oxidative stress in rat. General Physiology and Biophysics, 34(3), 263-275. Full Article

Sebai, H., Jabri, M. A., Souli, A., Rtibi, K., Selmi, S., Tebourbi, O., ... & Sakly, M. (2014). Antidiarrheal and antioxidant activities of chamomile (Matricaria recutita L.) decoction extract in rats. Journal of Ethnopharmacology, 152(2), 327-332. Full Article

Pereira, R. P., Fachinetto, R., de Souza Prestes, A., Puntel, R. L., Da Silva, G. N. S., Heinzmann, B. M., ... & Morsch, V. M. (2009). Antioxidant effects of different extracts from Melissa officinalis, Matricaria recutita and Cymbopogon citratus. Neurochemical Research, 34(5), 973-983. Full Article


Kobayashi, Y., Takahashi, R., & Ogino, F. (2005). Antipruritic effect of the single oral administration of German chamomile flower extract and its combined effect with antiallergic agents in ddY mice. Journal of Ethnopharmacology, 101(1-3), 308-312. Full Article

Kobayashi, Y., Nakano, Y., Inayama, K., Sakai, A., & Kamiya, T. (2003). Dietary intake of the flower extracts of German chamomile (Matricaria recutita L.) inhibited compound 48/80-induced itch-scratch responses in mice.Phytomedicine, 10(8), 657-664. Full Article


Koch, C., Reichling, J., Kehm, R., Sharaf, M. M., Zentgraf, H., Schneele, J., & Schnitzler, P. (2008). Efficacy of anise oil, dwarf‐pine oil and chamomile oil against thymidine‐kinase‐positive and thymidine‐kinase‐negative herpesviruses. Journal of Pharmacy and Pharmacology, 60(11), 1545-1550. Full Article


Viola, H., Wasowski, C., De Stein, M. L., Wolfman, C., Silveira, R., Dajas, F., ... & Paladini, A. C. (1995). Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects. Planta Medica, 61(03), 213-216. Full Abstract


Hajaji, S., Sifaoui, I., López-Arencibia, A., Reyes-Batlle, M., Jiménez, I. A., Bazzocchi, I. L., ... & Piñero, J. E. (2018). Leishmanicidal activity of α-bisabolol from Tunisian chamomile essential oil. Parasitology Research, 1-13. Full Article


Ranpariya, V. L., Parmar, S. K., Sheth, N. R., & Chandrashekhar, V. M. (2011). Neuroprotective activity of Matricaria recutita against fluoride-induced stress in rats. Pharmaceutical Biology, 49(7), 696-701. Full Article

Chandrashekhar, V. M., Ranpariya, V. L., Ganapaty, S., Parashar, A., & Muchandi, A. A. (2010). Neuroprotective activity of Matricaria recutita Linn against global model of ischemia in rats. Journal of Ethnopharmacology, 127(3), 645-651. Full Article


Zargaran, A., Borhani-Haghighi, A., Salehi-Marzijarani, M., Faridi, P., Daneshamouz, S., Azadi, A., ... & Mohagheghzadeh, A. (2018). Evaluation of the effect of topical chamomile (Matricaria chamomilla L.) oleogel as pain relief in migraine without aura: a randomized, double-blind, placebo-controlled, crossover study. Neurological Sciences, 1-9. Full Article


Sándor, Z., Mottaghipisheh, J., Veres, K., Hohmann, J., Bencsik, T., Horváth, A., ... & Csupor, D. (2018). Evidence supports tradition: the in vitro effects of Roman Chamomile on smooth muscles. Frontiers in Pharmacology, 9, 323. Full Article


Petronilho, S., Maraschin, M., Coimbra, M. A., & Rocha, S. M. (2012). In vitro and in vivo studies of natural products: A challenge for their valuation. The case study of chamomile (Matricaria recutita L.). Industrial Crops and Products, 40, 1-12. Full Article

Patient Reports

“Seems to help with sleep. Very convenient. I use it sublingually sometimes if I wake up too early” – C.T

“I really didn't expect this to work very well and was very pleased to find that it's really very effective and I only take three drops per night.” – M.J

"I use this every night and it works great for me, I don't feel that sleeping med drowsiness in the morning either."-R.I.

"Absolutely fantastic! Me and my teenage daughter couldn't cope without it. Closes off any 'brainwaves' and allows you to go to sleep within 20 minutes." -E.H.

Dosage Information

15 Drops in 4 oz. of water at bedtime.  Repeat during the night as needed. Can also be used at a dose of 10-15 drops during the day as needed for anxiety.

Safety Information

An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Babuna did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary. Full Article

OVER 20 YEARS OF NUTRACEUTICAL INNOVATION - Founded in 1993, Nutramedix supplies highly bioavailable nutritional supplements to health care professionals and consumers. A majority of Nutramedix profits are donated to charitable organizations.

All products are shipped from Cyprus with ACS Courier. For shipping to the rest of Europe and rest of the world, we use the EPG service of the Cyprus Post Office. --------------------- See shipping and delivery details below: --------------------- Destination Shipping cost Delivery time Cyprus ---------------------ACS Service €3.99 ---------------------FREE SHIPPING OVER €50 --------------------- 2-3 business days Rest of Europe EPG Service €9.90 --------------------- 5-15 business days Rest of the world EPG Service €9.90 7-20 business days --------------------- Important note: The delivery time may take longer during holidays. Information on customs: European citizens do not have to pay any customs since all of our products are shipped from Cyprus which is a member of the European Union. Customs duty is charged to non-EU countries when the package reaches the destination country. If your package is delivered to a non-EU country, you will be required to pay customs and/or duties fees in order to collect your package. Note that custom policies and import duties are different for each country. It is advisable to contact your country’s customs office before you proceed with purchasing from our store in order to be informed of all the amounts charged for purchasing the item of your choice.
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