ANTI-INFLAMMATORY
Jacobo‐Herrera, N. J., Vartiainen, N., Bremner, P., Gibbons, S., Koistinaho, J., & Heinrich, M. (2006). F‐κB modulators from Valeriana officinalis. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 20(10), 917-919. Full Article
ANTIOXIDANT
Кatsarova, М., Dimitrova, S., Lukanov, L., Sadakov, F., Denev, P., Plotnikov, E., ... & Kostadinova, I. (2017). Antioxidant activity and nontoxicity of extracts from Valeriana officinalis, Мelissa officinalis, Crataegus monogyna, Hypericum perforatum, Serratula coronatа and combinations Antistress 1 and Antistress 2. Full Article
Sudati, J. H., Vieira, F. A., Pavin, S. S., Dias, G. R. M., Seeger, R. L., Golombieski, R., ... & Barbosa, N. V. (2013). Valeriana officinalis attenuates the rotenone-induced toxicity in Drosophila melanogaster. Neurotoxicology, 37, 118-126. Full Article
Sudati, J. H., Fachinetto, R., Pereira, R. P., Boligon, A. A., Athayde, M. L., Soares, F. A., ... & Rocha, J. B. T. (2009). In vitro antioxidant activity of Valeriana officinalis against different neurotoxic agents. Neurochemical Research, 34(8), 1372. Full Article
ANXIOLYTIC
Murphy, K., Kubin, Z. J., Shepherd, J. N., & Ettinger, R. (2010). Valeriana officinalis root extracts have potent anxiolytic effects in laboratory rats. Phytomedicine, 17(8-9), 674-678. Full Article
Hattesohl, M., Feistel, B., Sievers, H., Lehnfeld, R., Hegger, M., & Winterhoff, H. (2008). Extracts of Valeriana officinalis L. s.l. show anxiolytic and antidepressant effects but neither sedative nor myorelaxant properties.Phytomedicine, 15(1-2), 2-15. Full Article
ANTICONVULSANT
Rezvani, M. E., Roohbakhsh, A., Allahtavakoli, M., & Shamsizadeh, A. (2010). Anticonvulsant effect of aqueous extract of Valeriana officinalis in amygdala-kindled rats: possible involvement of adenosine. Journal of Ethnopharmacology, 127(2), 313-318. Full Article
Carrasco, M. C., Vallejo, J. R., Pardo‐de‐Santayana, M., Peral, D., Martín, M. Á., & Altimiras, J. (2009). Interactions of Valeriana officinalis L. and Passiflora incarnata L. in a patient treated with lorazepam.Phytotherapy Research, 23(12), 1795-1796. Full Article
Hiller, K. O., & Zetler, G. (1996). Neuropharmacological studies on ethanol extracts of Valeriana officinalis L.: behavioural and anticonvulsant properties. Phytotherapy Research, 10(2), 145-151. Full Article
ANTIMICROBIAL
Letchamo, W., Ward, W., Heard, B., & Heard, D. (2004). Essential oil of Valeriana officinalis L. cultivars and their antimicrobial activity as influenced by harvesting time under commercial organic cultivation. Journal of Agricultural and Food Chemistry, 52(12), 3915-3919. Abstract
GABA RECEPTOR MODULATOR
Ortiz, J. G., Nieves-Natal, J., & Chavez, P. (1999). Effects of Valeriana officinalis extracts on [3 H] flunitrazepam binding, synaptosomal [3 H] GABA uptake, and hippocampal [3 H] GABA release. Neurochemical research, 24(11), 1373-1378. Full Article
IMPROVED SLEEP QUALITY
Barton, D. L., Atherton, P. J., Bauer, B. A., Moore Jr, D. F., Mattar, B. I., LaVasseur, B. I., ... & Morgenthaler, T. I. (2011). The use of valeriana officinalis (valerian) in improving sleep in patients who are undergoing treatment for cancer: a phase III randomized, placebo-controlled, double-blind study: NCCTG Trial, N01C5. The Journal of Supportive Oncology, 9(1), 24. Full Article
Murti, K., Kaushik, M., Sangwan, Y., & Kaushik, A. (2011). Pharmacological properties of Valeriana officinalis—a review. Pharmacologyonline, 3, 641-646. Full Article
Jacques Otobone, F., Colombo Martins, J. V., Trombelli, M. A., Andreatini, R., & Audi, E. A. (2005). Anxiolytic and sedative effects of a combined extract of Passiflora alata Dryander and Valeriana officinalis L. in rats. Acta Scientiarum. Health Sciences, 27(2). Full Article
Fernández, S., Wasowski, C., Paladini, A. C., & Marder, M. (2004). Sedative and sleep-enhancing properties of linarin, a flavonoid-isolated from Valeriana officinalis. Pharmacology Biochemistry and Behavior, 77(2), 399-404. Full Article
Leathwood, P. D., Chauffard, F., Heck, E., & Munoz-Box, R. (1982). Aqueous extract of valerian root (Valeriana officinalis L.) improves sleep quality in man. Pharmacology Biochemistry and Behavior, 17(1), 65-71. Full Article
RELAXANT
Caudal, D., Guinobert, I., Lafoux, A., Bardot, V., Cotte, C., Ripoche, I., ... & Huchet, C. (2018). Skeletal muscle relaxant effect of a standardized extract of Valeriana officinalis L. after acute administration in mice. Journal of Traditional and Complementary Medicine, 8(2), 335-340. Full Article
Pilerood, S. A., & Prakash, J. (2013). Nutritional and medicinal properties of valerian (Valeriana officinalis) herb: A review. International Journal of Food, Nutrition and Dietetics, 1(1), 25. Full Article
Occhiuto, F., Pino, A., Palumbo, D. R., Samperi, S., De Pasquale, R., Sturlese, E., & Circosta, C. (2009). Relaxing effects of Valeriana officinalis extracts on isolated human non‐pregnant uterine muscle. Journal of Pharmacy and Pharmacology, 61(2), 251-256. Full Article