FOR RESOLVING SULFITE AND SULFA DRUG TOXICITY

General Description

Sparga is an extract of the root of Asparagus officinalis and is used to resolve Sulfite and/or Sulfa drug toxicity. This condition appears to block the efficient production of reduced L-glutathione, thus inhibiting the body's ability to eliminate toxins. The problem with sulfite and sulfa drugs likely results from a genetic up-regulation of the Cystathionine-Beta-Synthase (CBS) enzyme or a genetic down-regulation of Sulfite Oxidase (SuOx). When this occurs, sulfite and sulfa drugs build up in that individual, blocking glutathione production and blocking uptake of lipoic acid and sulfur amino acids thus making detoxification inefficient, in which case the toxins that are held up in the body weaken the immune system and the organs, and the patient is predisposed to chronic infection. The CBS and/or SuOx genes may cause sulfites and sulfa drugs to build up to a high enough level in the body so as to possibly block the cell's ability to take up sulfur amino acids (cysteine, methionine, and taurine) as well as Glutathione and Lipoic Acid. The absence of these nutrients in the cells can impair detoxification from the cells.

Some Reported Medicinal Properties

ANTI-ARTHRITIC

ANTI-DIABETIC

ANTI-INFLAMMATORY

ANTIOXIDANT

ANTI-RHEUMATIC

ANTI-TUMOR

ANTI-VIRAL

APHRODISIAC

CYTOTOXIC

DIURETIC

HEPATOPROTECTIVE

NEUROPROTECTIVE

SEDATIVE

Research On NutraMedix Product

IN VIVO – ACUTE ORAL TOXICITY TESTS

An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Sparga did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary. Full Article

Medical Conditions [peer-reviewed journals]

CANCER

Bousserouel, S., Le Grandois, J., Gossé, F., Werner, D., Barth, S. W., Marchioni, E., ... & Raul, F. (2013). Methanolic extract of white asparagus shoots activates TRAIL apoptotic death pathway in human cancer cells and inhibits colon carcinogenesis in a preclinical model. International Journal of Oncology, 43(2), 394-404. Full Article

DIABETES

Hafizur, R. M., Kabir, N., & Chishti, S. (2012). Asparagus officinalis extract controls blood glucose by improving insulin secretion and β-cell function in streptozotocin-induced type 2 diabetic rats. British Journal of Nutrition, 108(9), 1586-1595. Full Article

Zhao, J., Zhang, W., Zhu, X., Zhao, D., Wang, K., Wang, R., & Qu, W. (2011). The aqueous extract of Asparagus officinalis L. by‐product exerts hypoglycaemic activity in streptozotocin‐induced diabetic rats. Journal of the Science of Food and Agriculture, 91(11), 2095-2099. Full Article

TUMOR

Wang, J., Liu, Y., Zhao, J., Zhang, W., & Pang, X. (2013). Saponins extracted from by‐product of Asparagus officinalis L. suppress tumour cell migration and invasion through targeting Rho GTPase signalling pathway. Journal of the Science of Food and Agriculture, 93(6), 1492-1498. Full Article

Huang, X. F., Lin, Y. Y., & Kong, L. Y. (2008). Steroids from the roots of Asparagus officinalis and their cytotoxic activity. Journal of Integrative Plant Biology, 50(6), 717-722. Full Article

Li, X. M., Cai, J. L., Wang, L., Wang, W. X., Ai, H. L., & Mao, Z. C. (2017). Two new phenolic compounds and antitumor activities of asparinin A from Asparagus officinalis. Journal of Asian natural products research, 19(2), 164-171. Full Article

Medicinal Properties [peer-reviewed journals]

ANTIFUNGAL

Wang, H., & Ng, T. B. (2001). Isolation of a novel deoxyribonuclease with antifungal activity from Asparagus officinalis seeds. Biochemical and Biophysical Research Communications, 289(1), 120-124. Full Article

Shimoyamada, M., Suzuki, M., Maruyama, M., & Watanabe, K. (1996). An antifungal saponin from white asparagus (Asparagus officinalis L) bottoms. Journal of the Science of Food and Agriculture, 72(4), 430-434. Full Article

Shimoyamada, M., Suzuki, M., Sonta, H., Maruyama, M., & Okubo, K. (1990). Antifungal activity of the saponin fraction obtained from Asparagus officinalis L. and its active principle. Agricultural and Biological Chemistry, 54(10), 2553-2557. Full Article

ANTIOXIDANT

Symes, A., Shavandi, A., Zhang, H., Mohamed Ahmed, I. A., Al-Juhaimi, F. Y., & Bekhit, A. E. D. A. (2018). Antioxidant Activities and Caffeic Acid Content in New Zealand Asparagus (Asparagus officinalis) Roots Extracts. Antioxidants, 7(4), 52. Full Article

Fan, R., Yuan, F., Wang, N., Gao, Y., & Huang, Y. (2015). Extraction and analysis of antioxidant compounds from the residues of Asparagus officinalis L. Journal of Food Science and Technology, 52(5), 2690-2700. Full Article

Lee, J. W., Lee, J. H., Yu, I. H., Gorinstein, S., Bae, J. H., & Ku, Y. G. (2014). Bioactive compounds, antioxidant and binding activities and spear yield of Asparagus officinalis L. Plant Foods for Human Nutrition, 69(2), 175-181. Full Article

Zhao, Q., Xie, B., Yan, J., Zhao, F., Xiao, J., Yao, L., ... & Huang, Y. (2012). In vitro antioxidant and antitumor activities of polysaccharides extracted from Asparagus officinalis. Carbohydrate Polymers, 87(1), 392-396. Full Article

Khorasani, A., Sani, W., Philip, K., Taha, R. M., & Rafat, A. (2010). Antioxidant and antibacterial activities of ethanolic extracts of Asparagus officinalis cv. Mary Washington: Comparison of in vivo and in vitro grown plant bioactivities. African Journal of Biotechnology, 9(49), 8460-8466. Full Article

Makris, D. P., & Rossiter, J. T. (2001). Domestic processing of onion bulbs (Allium cepa) and asparagus spears (Asparagus officinalis): effect on flavonol content and antioxidant status. Journal of Agricultural and Food Chemistry, 49(7), 3216-3222. Full Article

ETHONAL METABOLISM

Kim, B. Y., Cui, Z. G., Lee, S. R., Kim, S. J., Kang, H. K., Effects of Asparagus officinalis extracts on liver cell toxicity and ethanol metabolism Lee, Y. K., & Park, D. B. (2009).. Journal of Food Science, 74(7), H204-H208. Full Article

WEIGHT LOSS

Zhu, X., Zhang, W., Pang, X., Wang, J., Zhao, J., & Qu, W. (2011). Hypolipidemic Effect of n‐Butanol Extract from Asparagus officinalis L. in Mice fed a High‐fat Diet. Phytotherapy Research, 25(8), 1119-1124. Full Article

HEPATOPROTECTIVE

Zhu, X., Zhang, W., Zhao, J., Wang, J., & Qu, W. (2010). Hypolipidaemic and hepatoprotective effects of ethanolic and aqueous extracts from Asparagus officinalis L. by‐products in mice fed a high‐fat diet. Journal of the Science of Food and Agriculture, 90(7), 1129-1135. Full Article

VARIOUS PROPERTIES

Iqbal, M., Bibi, Y., Raja, N. I., Ejaz, M., Hussain, M., Yasmeen, F., ... & Imran, M. (2017). Review on Therapeutic and Pharmaceutically Important Medicinal Plant Asparagus officinalis L. Journal of Plant Biochemistry and Physiology, 5, 180. Full Article

Conference Presentations

Cowden Support Program for Lyme: Observational Study – Dublin, Ireland – June, 2012 Armin Schwarzbach, MD PhD Full Video

Patient Reports

"I tried detoxes before, but my detox pathways were blocked. After starting Sparga, the toxins were being eliminated quickly. Sparga helped me recalibrate my whole body and my weight and joint pain dropped and my skin cleared up! Sparga is really amazing!” -O.N.

“I have used Sparga Sulphur Detox by NutraMedix for 10 months. Recommended by my MD to help with detoxifying from 9 months of daily IV treatments. Wonderful product. Love NutraMedix.” – A.N

“Sparga Sulphur Detox by NutaMedix helps so much for those of us fighting chronic illnesses! Can always count on this company!” – e A.P

“I used 10 drops 2x per day to lower my urine sulfate level and Sparga Sulphur Detox by NutraMedix has reduced my level in just 3 days.” -P.S.

“I have Lyme disease that manifests as Rheumatoid arthritis. The Asparagus extract does seem to help quite a bit.” -P.U.

Dosage Information

10 drops twice daily for 3-4 months helps to resolve Sulfite and/or Sulfa drug toxicity.

Safety Information

An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Sparga did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary. Full Article

Nutramedix, SPARGA-SULPHUR DETOX Nutramedix, SPARGA-SULPHUR DETOX