Nutramedix, QUINA -MICROBIAL DEFENSE Nutramedix, QUINA -MICROBIAL DEFENSE

Quina is an extract produced from the bark of Cinchona calisaya, a tree from South America that is found between 1,400 meters and 2,800 meters above sea level.  Quina has been used for centuries by native South Americans to treat a number of illnesses including malaria, cancer, fever, dysentery, typhoid, pneumonia, etc. It was one of the first South American medicinal plants to become known outside of the Americas. It was first used in Europe in the mid- 1600's and recognized by the British Pharmacopoeia in 1677. Quinine, one of the four alkaloids in Quina known to have antimalarial properties, has been used to produce medicines to treat malaria for nearly 200 years. Malaria strains have mutated rendering these drugs far less effective causing researchers to re-evaluate the medicinal properties of whole plant extracts of Cinchona species such as Quina. 

Quina is utilized by some health care professionals in the U.S. as an important component of a Lyme disease protocol. It has been found to be very effective in treating Borrelia burgdorferi, the bacteria that causes Lyme disease, Babesia and many of the coinfections that are usually associated with this condition.

ANTIARRHYTHMIC

ANTIPYRETIC

ANTISPASMODIC

ANTIFUNGAL

ANTIPARASITIC

ANTIBACTERIAL

AMEBICIDE

ANALGESIC ASTRINGENT

DIGESTIVE

FEBRIFUGE

NERVINE

NEURASTHENIC

MALARIA

Carroll, A. M., Kavanagh, D. J., McGovern, F. P., Reilly, J. W., & Walsh, J. J. (2012). Nature’s Chiral Catalyst and Anti-Malarial Agent: Isolation and Structure Elucidation of Cinchonine and Quinine from Cinchona calisaya. Journal of Chemical Education, 89(12), 1578-1581.  Full Article

Frankenburg, F. R., & Baldessarini, R. J. (2008). Neurosyphilis, malaria, and the discovery of antipsychotic agents. Harvard Review of Psychiatry, 16(5), 299-307. Full Article

Botsaris, A. S. (2007). Plants used traditionally to treat malaria in Brazil: the archives of Flora Medicinal. Journal of Ethnobiology and Ethnomedicine, 3(1), 18. Full Article

Andrade-Neto, V. F., Brandão, M. G. L., Stehmann, J. R., Oliveira, L. A., & Krettli, A. U. (2003). Antimalarial activity of Cinchona-like plants used to treat fever and malaria in Brazil. Journal of Ethnopharmacology, 87(2-3), 253-256. Full Article

Munoz, V., Sauvain, M., Bourdy, G., Callapa, J., Rojas, I., Vargas, L., ... & Deharo, E. (2000). A search for natural bioactive compounds through a multidisciplinary approach in Bolivia. Part II. Antimalarial activity of some plants used by Mosetene indians. Journal of Ethnopharmacology, 69(2), 139-155. Full Article

ANTI-DIABETIC

Ezekwesili, C. N., Ogbunugafor, H. A., & Ezekwesili–Ofili, J. O. (2012). Anti-diabetic activity of aqueous extracts of Vitex doniana leaves and Cinchona calisaya bark in alloxan–induced diabetic rats. Int J Trop Disease, 2(4), 290-300. Full Article

ANTIMICROBIAL

Kushwah, P., Das, P., Badore, N. S., Salvekar, V., & Deshmukh, N. (2016). Evaluation of antimicrobial activity of Cinchona calisaya bark on Staphylococcus by agar well diffusion method. Pharmaceutical and Biological Evaluations, 3(2), 272-274. Full Article

VARIOUS PROPERTIES

Frankenburg, F. R., & Baldessarini, R. J. (2008). Neurosyphilis, malaria, and the discovery of antipsychotic agents. Harvard review of psychiatry, 16(5), 299-307. Full Article

A Hidden Epidemic: Integrative Treatment of Lyme Disease, Scott Forsgren, March 2009 Full Article

"I take this for babesiosis, and it is very effective. I respond better to it than the antimalarials such as Mepron, Atavaquone. Not as hard on my system, either. Started with one drop twice a day and worked up to ten. I have never taken more than ten drops twice a day (although you can). You put it in water, wait one minute, then drink. I haven't suffered any side effects from Quina and never had a severe herx reaction from it, either."-S.A.

“This has cleared up my foggy brain. I remember names and numbers again. My chronique fatigue has gone away . Not bad for a 70 year old gal.” – K.C

"Bloating, gas, stomach spasms – I had it all.  This stuff made me feel like I did when I was a kid.  My food was no longer my enemy.  Quina's great!"-R.I.

30 drops twice daily at least 30 minutes before meals (start with 1 drop in 4 oz. of water adding a drop with each dose).

An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Quina did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary. Full Article

Quina is an extract produced from the bark of Cinchona calisaya, a tree from South America that is found between 1,400 meters and 2,800 meters above sea level.  Quina has been used for centuries by native South Americans to treat a number of illnesses including malaria, cancer, fever, dysentery, typhoid, pneumonia, etc. It was one of the first South American medicinal plants to become known outside of the Americas. It was first used in Europe in the mid- 1600's and recognized by the British Pharmacopoeia in 1677. Quinine, one of the four alkaloids in Quina known to have antimalarial properties, has been used to produce medicines to treat malaria for nearly 200 years. Malaria strains have mutated rendering these drugs far less effective causing researchers to re-evaluate the medicinal properties of whole plant extracts of Cinchona species such as Quina. 

Quina is utilized by some health care professionals in the U.S. as an important component of a Lyme disease protocol. It has been found to be very effective in treating Borrelia burgdorferi, the bacteria that causes Lyme disease, Babesia and many of the coinfections that are usually associated with this condition.

ANTIARRHYTHMIC

ANTIPYRETIC

ANTISPASMODIC

ANTIFUNGAL

ANTIPARASITIC

ANTIBACTERIAL

AMEBICIDE

ANALGESIC ASTRINGENT

DIGESTIVE

FEBRIFUGE

NERVINE

NEURASTHENIC

MALARIA

Carroll, A. M., Kavanagh, D. J., McGovern, F. P., Reilly, J. W., & Walsh, J. J. (2012). Nature’s Chiral Catalyst and Anti-Malarial Agent: Isolation and Structure Elucidation of Cinchonine and Quinine from Cinchona calisaya. Journal of Chemical Education, 89(12), 1578-1581.  Full Article

Frankenburg, F. R., & Baldessarini, R. J. (2008). Neurosyphilis, malaria, and the discovery of antipsychotic agents. Harvard Review of Psychiatry, 16(5), 299-307. Full Article

Botsaris, A. S. (2007). Plants used traditionally to treat malaria in Brazil: the archives of Flora Medicinal. Journal of Ethnobiology and Ethnomedicine, 3(1), 18. Full Article

Andrade-Neto, V. F., Brandão, M. G. L., Stehmann, J. R., Oliveira, L. A., & Krettli, A. U. (2003). Antimalarial activity of Cinchona-like plants used to treat fever and malaria in Brazil. Journal of Ethnopharmacology, 87(2-3), 253-256. Full Article

Munoz, V., Sauvain, M., Bourdy, G., Callapa, J., Rojas, I., Vargas, L., ... & Deharo, E. (2000). A search for natural bioactive compounds through a multidisciplinary approach in Bolivia. Part II. Antimalarial activity of some plants used by Mosetene indians. Journal of Ethnopharmacology, 69(2), 139-155. Full Article

ANTI-DIABETIC

Ezekwesili, C. N., Ogbunugafor, H. A., & Ezekwesili–Ofili, J. O. (2012). Anti-diabetic activity of aqueous extracts of Vitex doniana leaves and Cinchona calisaya bark in alloxan–induced diabetic rats. Int J Trop Disease, 2(4), 290-300. Full Article

ANTIMICROBIAL

Kushwah, P., Das, P., Badore, N. S., Salvekar, V., & Deshmukh, N. (2016). Evaluation of antimicrobial activity of Cinchona calisaya bark on Staphylococcus by agar well diffusion method. Pharmaceutical and Biological Evaluations, 3(2), 272-274. Full Article

VARIOUS PROPERTIES

Frankenburg, F. R., & Baldessarini, R. J. (2008). Neurosyphilis, malaria, and the discovery of antipsychotic agents. Harvard review of psychiatry, 16(5), 299-307. Full Article

A Hidden Epidemic: Integrative Treatment of Lyme Disease, Scott Forsgren, March 2009 Full Article

"I take this for babesiosis, and it is very effective. I respond better to it than the antimalarials such as Mepron, Atavaquone. Not as hard on my system, either. Started with one drop twice a day and worked up to ten. I have never taken more than ten drops twice a day (although you can). You put it in water, wait one minute, then drink. I haven't suffered any side effects from Quina and never had a severe herx reaction from it, either."-S.A.

“This has cleared up my foggy brain. I remember names and numbers again. My chronique fatigue has gone away . Not bad for a 70 year old gal.” – K.C

"Bloating, gas, stomach spasms – I had it all.  This stuff made me feel like I did when I was a kid.  My food was no longer my enemy.  Quina's great!"-R.I.

30 drops twice daily at least 30 minutes before meals (start with 1 drop in 4 oz. of water adding a drop with each dose).

An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Quina did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary. Full Article